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pentobarbital will reduce the extent or influence of zolpidem by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unfamiliar.Contraindicated (one)pentobarbital decreases levels of panobinostat by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Sturdy CYP3A4 inducers can lower panobinostat concentrat